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Laboratoire Hra Pharma · Ulipristal Acetate

Ella: invented in a government lab

NIH scientists invented the technology behind Ella, and the government licensed it to Laboratoire HRA Pharma. NIH (its own scientists) reported a patent on it to NIH as an invention made with NIH grant money.
Invented in a government labPatent reported as grant-funded
Reported

–

Medicare paid, 2025

before rebates

Calculated

–

Medicare, 2020–2025

Reported

–

Medicare, 2026 Q1

the newest quarter CMS has published

Reported

$126K

NIH grants behind the patents

whole-grant totals, not the drug's cost

The public record, link by link

  1. 1 · Public research

    Invented in NIH labs and licensed to Laboratoire HRA Pharma.
  2. 2 · Patent

    Patents 9283233, 9616073, 10159681, licensed by NIH.
  3. 3 · FDA approval

    Approved Aug 13, 2010, sold by Laboratoire Hra Pharma (NDA 022474).
  4. 4 · Public pays

    Medicaid paid $5.2M in 2024. Medicare's 2025 drug files do not list it.

The government license

From NIH Technology Transfer's list of FDA-approved products built on licenses from NIH, CDC or FDA labs.
  • NIH to Laboratoire HRA Pharma

    A progesterone agonist/antagonist emergency contraceptive indicated for prevention of pregnancy following unprotected intercourse or a known or suspected contraceptive failure.

    First sold 2016. Licensed patents: US 9283233, US 9616073, US 10159681. See the list

The grants

Totals are everything NIH paid on each grant since 1985. A grant usually funded more than this one invention.
  • Steroid Hormone Action In Female Reproduction

    ZIADK075118 · National Institute of Diabetes and Digestive and Kidney Diseases · NIDDK, NIH's own lab · 2016–2021

    $126K

The patents

Patents the FDA lists for this drug that were also reported to NIH as grant-funded inventions.
  • US 9283233

    Method for on-demand contraception

    Reported by NIH (its own scientists)

    FDA-listed expiry Apr 13, 2030

Laboratoire Hra Pharma's side

Drug makers pay for the clinical trials that take a compound from the lab to FDA approval, and they pay royalties on licensed patents. Those terms are not public. Laboratoire Hra Pharma's page shows its other products on this list, its federal awards, its PAC's giving and its lobbying. If Laboratoire Hra Pharma wants to add its account, we will publish it here.

How this is built. A product is listed for one of two public records. Either NIH's Technology Transfer office lists it as an FDA-approved product built on a license from an NIH, CDC or FDA lab, or a patent the FDA lists for the drug was reported to NIH as an invention made with NIH grant money, as the Bayh-Dole Act requires. We then add what Medicare Part D, Part B and Medicaid paid for each product, and for each company, the federal grants and contracts it received, its PAC's donations and its lobbying.

What the numbers mean. Medicare and Medicaid figures are gross spending before the rebates drug makers pay back, which are confidential. Hospital-administered therapies such as CAR-T cell treatments are mostly paid under Medicare Part A and do not appear in these files. "NIH grants" is everything NIH paid on the grants a patent was reported under, from 1985 on; a grant usually paid for more than one invention, so it is not the cost of the drug. Federal contracts include purchases, such as vaccine doses, as well as research. Companies also paid for the clinical trials that took these products to approval. None of these figures shows that public money set a price or bought a decision.

Sources: NIH Technology Transfer: FDA-approved products licensed from NIH, CDC and FDA labs; NIH RePORTER patents reported under NIH grants (from iEdison); NIH RePORTER project funding; FDA Orange Book patent, exclusivity and product files; CMS Medicare Part D and Part B Spending by Drug (annual and quarterly); CMS Medicaid Spending by Drug; USAspending.gov federal grants and contracts. Updated 2026-11-06.